WCC-2022

Program

Time: July 22-24, 2023

Venue: Catalonia Barcelona Plaza, Spain

Keynote Forum
Time: 09:10-12:10, July 22, 2023 (Saturday); Place: Catalonia Barcelona Plaza, Spain

*Moderator*	To Be Confirmed Soon

09:10-09:15	*Moderator's Introduction***
09:15-09:40	*Title:* The Origin of Bladder Cancer *Dr. Bogdan Czerniak,* Professor, The University of Texas M. D. Anderson Cancer Center, USA
09:40-10:05	*Title:* TBD *Dr. Russel J. Reiter,* Professor, University of Texas Health Science Center, USA
10:05-10:30	*Title:* TBD *Mr. Tim Shinbara,* Vice President and CTO, The Association for Manufacturing Technology, USA
10:30-10:55	*Title:* TBD *Dr. James Wang,* Professor and Director of the eVTOL Research & Innovation Centre, Nanyang Technological University, Singapore
10:55-1120	*Title:* TBD *Dr. Hans-Jorg Fecht,* Chaired Professor and Director, Ulm University, Germany
11:20-11:45	*Title:* TBD *Dr. Samuel Kenig,* Professor, Vice President and Director of the Research and Development Authority, Shenkar College of Engineering and Design, Israel
11:45-12:10	*Title:* Prospects for Targeted Protein Degraders in the Fight Against Aggressive Cancer *Dr. Vehary SAKANYAN,* Professor, Nantes University, ProtNeteomix, France

WCC 01: Cancer Cell Biology & Genetics
Time: 14:00-18:20, July 22, 2023 (Saturday); Place: Catalonia Barcelona Plaza, Spain

*Chair*	*Dr. Rony Seger*, Professor, Weizmann Institute of Science, Israel
*Co-Chair*	*Dr. Xin Wang,* Associate Professor, The Chinese University of Hong Kong, Hong Kong of China

14:00-14:05	*Chair's Introduction*
14:05-14:25	*Keynote Speech* *Title: The Nuclear Translocation of ERK as a Therapeutic Target for Cancer and Inflammation* *Dr. Rony Seger*, Professor, Weizmann Institute of Science, Israel
14:25-14:45	*Title:* TBD *Dr. Loannis Papasotiriou,* Medical Director, R.G.C.C. INTERNATIONAL GmbH, Switzerland
14:45-15:05	*Title:* The Molecular Signature of Metastasis in the Early Stages of Clear Cell Renal Cell Carcinoma *Dr. Xinhua Zhu,* Associate Professor, Northwell Health Cancer Institute, USA
15:05-15:25	*Title:* The Ubiquitin-Independent Protein Degradation Pathway In Cancer Progression *Dr. Henry James Li,* Professor of Biochemistry, New York University-Shanghai, China
15:25-15:45	*Title:* Elucidating Osteoclast-Breast Tumor Hybrids Cell Fusion Mechanisms for Bone Metastatic Disease Progression *Dr. Kwan T. Chow,* City University of Hong Kong, China
15:45-16:00	*Coffee Break*
16:00-16:20	*Title:* Dissecting the Molecular Heterogeneity of Young-onset Colorectal Cancer *Dr. Xin Wang,* Associate Professor, The Chinese University of Hong Kong, Hong Kong, China
16:20-16:40	*Title:* Human RNASET2: A Highly Pleiotropic Tumor Suppressor Gene Involved in Establishing a Complex Crosstalk between Cancer Cells and the Tumor Microenvironment *Dr. Francesco Acquati,* Associate Pofessor, University of Insubria, Italy
16:40-17:00	*Title:* Intricating Membrane Transport and Metabolism with Intracellular pH Regulation. Insights into Mechanisms, Robustness, And Functional Redundancy *Dr. Laurent Counillon,* Professor, Université Nice-Sophia Antipolis, France
17:00-17:20	*Title:* Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis *Dr. Da Jung Kim*, Director of Metabolomics Core facility, Seoul National University Hospital, South Korea
17:20-17:40	*Title*: The Role of Genomic Structural Variants in Prognosis and Treatment of Cancer *Dr. James R. Broach*, Distinguished Professor and Chair, Penn State College of Medicine, USA
17:40-18:00	*Title:* The p 207 S LysRS–Ap₄A–Hint-1–MITF Pathway in Health and Diseases *Dr. Ehud Razin,* Professor, Hebrew University Hadassah Medical School, Israel
18:00-18:20	*Speech Opportunity Available*

WCC 02: Anti-Cancer Drug Discovery and Development
Time: 08:30-12:30, July 23, 2023 (Sunday); Place: Catalonia Barcelona Plaza, Spain

*Chair*	*Dr. Pran K. Datta,* Professor, University of Alabama at Birmingham, USA
*Co-Chair*	*Dr. Lixin Rui,* Associate Professor, University of Wisconsin-Madison, USA

08:30-08:35	*Chair's Introduction*
08:35-08:55	*Title:* TBD *Dr. Zvi Naor,* Professor, Tel Aviv University, Israel
08:55-09:15	*Title:* Ablation rate and Thyroglobulin Decrease after Low-dose 131-I in Differentiated Thyroid Carcinoma Post-Total Thyroidectomy at Vietnam National Cancer Hospital *Dr. Duong Duc Binh,* National Cancer Hospital (K hospital), Hanoi, Vietnam
09:15-09:35	*Title:* Anticancer Activity of Selected Plants of Israel and Palestine *Dr. Abdullatif Azab,* Researcher, Eastern Plants Company, Israel
09:35-09:55	*Title:* ME-503 for Immune-Oncology Treatment: A Novel Mode of Action *Dr. Hans Lentzen,* Managing Director, MELEMA Pharma GmbH, Germany
09:55-10:15	*Title:* Targeting Ibrutinib Resistance in B Cell Lymphoma *Dr. Lixin Rui,* Associate Professor, University of Wisconsin-Madison, USA
10:15-10:30	*Coffee Break*
10:30-10:50	*Title:* Molecular Mechanisms of Colon Tumorigenesis and Chemoresistance *Dr. Pran K. Datta,* Professor, University of Alabama at Birmingham, USA
10:50-11:10	*Title:* Chemo-Immunotherapy of Nanomedicine and anti-PD-1 antibody for Reprogramming Tumor Microenvironment to Overcome anti-PD-1 antibody-Resistance *Dr.* *Hiroaki Kinoh,* Principal Researcher, Innovation Center of NanoMedicine, Japan
11:10-11:30	*Title:* Finding a Potential Prognostic Biomarker with Analyzing A Serum Soluble CD26/DPP4 Titer Variation from Baseline in Cancer Treatment on Patients with CD26⁺Tumor in Phase I and Phase I/II Clinical Trials by a Humanized anti-CD26 Monoclonal Antibody Therapy *Dr. Yutaro* *Kaneko,* CEO, Juntendo University, Tokyo, Japan
11:30-11:50	*Title:* TBD *Dr. Dorit Avni,* Sphingolipids, MIGAL - Galilee Research Institute, Israel
11:50-12:10	*Title:* Anti Cancer : Rational Design by Trojan Horse Strategy *Dr. Nohad Al* *Omar,* College of Pharmacy, Knowledge university, Iraq
12:10-12:30	*Speech Opportunity Available*

WCC 03: Cancer Therapy & Treatments-Part I
Time: 08:30-12:10, July 23, 2023 (Sunday); Place: Catalonia Barcelona Plaza, Spain

*Chair*	*Dr. Hariprasad Vankayalapati,* Chief Scientific Officer, Biolexis Therapeutics, Inc., USA
*Co-Chair*	*Dr. Zhirui Wang*, Associate Professor, University of Colorado Anschutz Medical Campus, USA

08:30-08:35	*Chair's Introduction*
08:35-08:55	*Title:* Haemorrhagic Small Bowel Melanoma Metastasis: A Clinical Rarity *Dr. Alexandros Zoumpos,* Physician, Helios Klinik Herzberg/Osterode, Germany
08:55-09:15	*Title:* Measurement of Small Blood and Lymphatic Vessels in the Brain Using Novel MRI Techniques *Dr. Jun Hua,* Associate Professor, Johns Hopkins University School of Medicine, USA
09:15-09:35	*Title:* Efficacy of Electrochemotherapy in the Treatment of Cutaneous Melanoma Metastases and Rare Non-melanoma Skin Cancer *Dr. Serena Sestini*, Regional Melanoma Referral Center, USA
09:35-09:55	*Title:* Manufacturing Control of Investigational CAR-T- cell products: Standards, Guidelines and Opportunities *Dr. Devanjan Sikder*, Associate Director, Memorial Sloan-Kettering Cancer Center, USA
09:55-10:15	*Title:* CCR4-IL2 Bispecific Immunotoxin for Targeted Therapy of Cutaneous T-Cell Lymphoma *Dr. Zhirui Wang*, Associate Professor, University of Colorado Anschutz Medical Campus, USA
10:15-10:30	*Coffee Break*
10:30-10:50	*Title:* Labyrinthin Moves from Bench-To-Clinic as Both Neo- And Pan-Adenocarcinoma Target *Dr. Michael Babich,* Co-Founder and CEO, LabyRx Immuno-Oncology, Sacramento, USA
10:50-11:10	*Title:* Mechanisms underlying Heterogeneous Outcome of Immune Checkpoint Inhibitors in Mouse HNSCC Models *Dr. Jing H*. Wang, Professor, UPMC Hillman Cancer Center, University of Pittsburgh, USA
11:10-11:30	*Title:* AI/ML Driven Discovery and Development of Cancer Immunotherapeutics Through Small Molecules and Targeted Protein Degraders *Dr. Hariprasad Vankayalapati,* Chief Scientific Officer, Biolexis Therapeutics, Inc., USA
11:30-11:50	*Title:* A Novel Genetically Engineered Blood System for Cancer Therapy *Dr. James Che-Kun Shen,* Chair Professor, Taipei Medical University, Taipei, Taiwan
11:50-12:10	*Speech Opportunity Available*

WCC 04: Clinical Oncology
Time: 14:00-18:20, July 23, 2023 (Sunday); Place: Catalonia Barcelona Plaza, Spain

*Chair*	*Dr. Junichi Arita,* Professor, Department of Gastroenterological Surgery, Akita University, Japan
*Co-Chair*	*Dr. Andrew H Rodgers,* Director of Regulatory & Analytical Affairs, Dekk Tec. Inc., USA

14:00-14:05	*Chair's Introduction*
14:05-14:25	*Title:* Female Students’ Knowledge, Beliefs, Attitude and Practice of Breast Self-Examination in a University in the Western Cape *Ms.* *Mavis Bobie Ansah*, Oncology Nurse Specialist, Komfo Anokye Teaching Hospital, Ghana
14:25-14:45	*Title:* Hepatic Resections an Liver Transplantation: Signaling Pathways Involved in Protection Against Hepatic Ischemia-Reperfusion Damage and Liver Regeneration Failure: role of liver-adipose tissue axis *Dr. Carmen Peralta,* Senior Group Leader, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Spain
14:45-15:05	*Title:* Repeat Resection of Neuroendocrine Liver Metastases and Possibility of Cure *Dr. Junichi Arita,* Professor, Department of Gastroenterological Surgery, Akita University, Japan
15:05-15:25	*Title:* Systemic Chemotherapy for Soft Tissue Sarcoma Rather than Liver, Pancreatic And Biliary Tract Cancer *Dr. Hiroyuki Narahara,* Director of Clinical Research Center, Hyogo Prefectural Nishinomiya Hospital, Japan
15:25-15:45	*Title:* ROS Homeostasis and Metabolism: A Double-Edged Sword in Hepatocellular Carcinoma *Dr. Eunyoung Tak*, Associate Professor, University of Ulsan College of Medicine, South Korea
15:45-16:00	*Coffee Break*
16:00-16:20	*Title:* Impact of Viral Burden and Trajectory of Hepatocellular Carcinoma in Armenia *Dr. Hasmik Ghazinyan*, Nork Clinical Hospital of Infectious Diseases, Yerevan , Armenia
16:20-16:40	*Title:* Reconstructive Surgery of the Upper Lip after Combined Resection of the Upper Lip and Buccal Mucosa for Oral Cancer *Dr.* *Kazuhide Matsunaga,* Associate Professor, Osaka University, Japan
16:40-17:00	*Title:* Up-date: Use of 4-demethyl-4-cholesteryloxycarbonyl-penclomedine (DM-CHOC-PEN) as Therapy for Advanced Non-Small Cell Lung Cancer (NSCLC) Involving the CNS *Dr. Andrew H Rodgers*, Director of Regulatory & Analytical Affairs, Dekk Tec. Inc., USA
17:00-17:20	*Title:* Advanced Oral Cancers Surgical Management *Dr. Harsh Dhar*, Consultant Head Neck and Skull Base Surgeon, Medica Superspeciality Hospitals & Cancer Centre, India
17:20-17:40	*Title:* Rare Cutaneous Tumors: A Case Report of Angiosarcoma and Primary Cutaneous Lymphoma *Dr. Typhannie Coelho Borges Silva,* Tocantinense University Center Presidente Antônio Carlos - UNITPAC, Brazil
17:40-18:00	*Title:* Updates in Thyroid Nodules Management *Dr. Thanh D. Hoang,* Program Director, Walter Reed National Military Medical Center, USA
18:00-18:20	*Speech Opportunity Available*

WCC 05: Cancer Therapy & Treatments-Part II
Time: 08:30-12:10, July 24, 2023 (Monday); Place: Catalonia Barcelona Plaza, Spain

*Chair*	*Dr. Thomas Böldicke,* Senior Scientist, Department Structure and Function of Proteins, Helmholtz Centre for Infection Research, Germany
*Co-Chair*	*Dr. Jerome H. Check,* Professor, Cooper Medical School of Rowan University, USA

08:30-08:35	*Chair's Introduction*
08:35-08:55	*Title: Treatment with Progesterone Antagonists May Be the Key to Converting Many End-Stage Cancers Into a Chronic Disease With Low Morbidity* *Dr. Jerome H. Check,* Professor, Cooper Medical School of Rowan University, USA
08:55-09:15	*Title:* Targeting Microtubule Stabilization to Reduce Breast Cancer Metastasis *Dr. Stuart S. Martin,* Deputy Director, Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, USA
09:15-09:35	*Title:* Absorbed Dose and Its Determination in Hadrontherapy *Dr.* *Grazia Gambarini*, Associate Professor, Department of Physics, Università degli Studi di Milano, National Institute of Nuclear Physics (INFN), Section of Milano, Italy
09:35-09:55	*Title:* Therapeutic Inhibitors of Progression of Neuroblastoma Cells *Dr. Nada Al-Hasawi*, Kuwait University, Kuwait
09:55-10:15	*Title:* Triple Negative Breast Cancer Therapy: A Novel Approach *Dr.* *Antonio Ponzetto,* Retired Professor of Gastroenterology University of Torino, Torino, Italy
10:15-10:30	*Coffee Break*
10:30-10:50	*Title:* Mature TERATOMA in the Right Ventricle *Dr. Fekede D Agwa*r, Addis Ababa University, Ethiopia
10:50-11:10	*Title:* The Role of SNAIL 1 and SNAIL 2 Transcriptional Factors in the Development Of Ovarian Cancer Cells’ Chemoresistance in the Context of Their Metastatic Potential *Dr. Michal Kielbik,* Assistant Professor, Institute of Medical Biology, Polish Academy of Sciences, Poland
11:10-11:30	*Title:* Pigmented Lesion on the Face: Which is The Chance of Being Melanoma Using Reflectance Confocal Microscopy Features *Dr. Fernanda Mendes,* Physician, AC Camargo Cancer Cente, Brazil
11:30-11:50	*Title:* Therapeutic Potential of Intrabodies Against Neoantigens: Current Status And Future Directions *Dr. Thomas Böldicke,* Senior Scientist, Department Structure and Function of Proteins, Helmholtz Centre for Infection Research, Germany
11:50-12:10	*Speech Opportunity Available*

WCC 06: Oncology Nursing and Prevention
Time: 14:00-18:00, July 24, 2023 (Monday); Place: Catalonia Barcelona Plaza, Spain

*Chair*	*Dr. Jacqueline T. Norrell,* Director, Rutgers Cancer Institute, USA

14:00-14:05	*Chair's Introduction*
14:05-14:25	*Title:* Complexity of Care and Nursing Management of Toxicities in Cancer Patients Receiving Immunotherapy Including Cellular Therapy Treatments: The New Phenotype *Dr. Jacqueline T. Norrell,* Director, Rutgers Cancer Institute, USA
14:25-14:45	*Title: Improving Medication Adherence and Symptom Management in Patients with Cancer* *Dr. Carla Schaefer,* Associate Chief Nursing Officer, The State University of New Jersey, USA
14:45-15:05	*Title:* Innovation in Ambulatory Cancer Care-Memorial Sloan Kettering Cancer Center *Dr. Geema Shetty Masson,* Associate Attending Anesthesiologist, Memorial Sloan Kettering Cancer Center, USA
15:05-15:25	*Title:* Outpatient Palliative Care for Advance Cancer Patients: Implementation of a Day Hospital *Dr.* *Laura Thery*, Consultant, Institut Curie, France
15:25-15:45	*Title:* Coping Strategies and Their Impact on Emotional Distress and Fatigue Among Breast Cancer Survivors *Dr. Inbar Levkovich*, Associate Professor, Oranim Academic College of Education, Israel
15:45-16:00	*Coffee Break*
16:00-16:20	*Title*: Cognitive deficits and psychopathological symptoms among children with medulloblastoma *Dr. Annamária Szentes,* Clinical Child Psychologist, 2nd Department of Paediatrics, Semmelweis University, Hungary
16:20-16:40	*Title*: Epidemiology of Breast Cancer In Women Based On Diagnosis Data From Oncologists And Senologists In Algeria *Dr. A Boudjella*, Blida 1 University, Algeria
16:40-17:00	*Title:* Combining the American Thyroid Association's Ultrasound Classification with Cytological Subcategorization Improves the Assessment of Malignancy Risk in Indeterminate Thyroid Nodules *Dr. Aline Machado Larcher de Almeida,* School of Medicine of Federal University of Rio de Janeiro, Brazil
17:00-17:20	*Title:* Production and Prebiotic Properties of Oligofructans from Sugarcane Juice Fermentation by Bacillus subtilis TISTR 001 *Dr. Boontiwa Ninchan,* Assistance Professor, Sugars and Derivatives Analytical Laboratory, Department of Biotechnology, Faculty of Agro-Industry, Kasetsart University, Thailand
17:20-17:40	*Title:* The Impact of Social Vulnerability on Time to Treatment Disparities Among Insured Adult Patients with Metastatic Cancers *Dr. Teresa M. Zyczynsk*, Director, Customer Strategy & Solutions, Bristol-Myers Squibb, USA
17:40-18:00	*Speech Opportunity Available*

Video
1	*Title:* Predicting Response to Immunotherapy in Head and Neck Cancer *Dr. Priyanka Bhateja,* Assistant Professor, The Ohio State University, USA
2	*Title:* TBD *Dr. Zoe S. Walters,* Lecturer, Southampton University, USA
3	*Title:* Molecular Iodine in Chemoresistant Cancers *Dr.* *Carmen Aceves,* Universidad Nacional Autómona de México, México
4	*Title:* TRIM32 Promotes Radioresistance by Disrupting TC45-STAT3 Interaction in Triple-Negative Breast Cancer *Dr. Jianming Tang*, Zhejiang Provincial People' s Hospital, People' s Hospital of Hangzhou Medical College, China
5	*Title:* TBD *Dr. Yonglei Liu,* Zhongshan Hospital Qingpu Branch, Fudan University, China
6	*Title:* Assessment of Extremely Low Frequency Electromagnetic Field Exposure In Children In Residential Settings through Machine Learning *Dr.* *Gabriella Tognola*, Cnr-Istituto di Elettronica e di Ingegneria dell’Informazione e delle Telecomunicazioni (CNR-IEIIT) Milano, Italy
7	*Title:* Transdermal Buprenorphine for the Treatment of Radiation-Induced Mucositis Pain in Head and Neck Cancer Patients - Full Text View - ClinicalTrials.gov *Dr. Aditya Shreenivas,* Assistant Professor, Medical College of Wisconsin, USA
9	*Title:* Repeat periods of electrical stimulation prolong the modulation of the micturition reflex in the rat *Dr. Chonghe Jiang,* The Sixth Affiliated Hospital of Guangzhou Medical University, China
10	*Title:* TBD *Dr.* *Mohammed Abdulaziz Aldawish*, PSMMC, Saudi Arabia