BIT's 8th Annual World Congress of Molecular & Cell Biology (CMCB-2018)
★ Scientific Program
BIT's 8th Annual Congress of

Molecular & Cell Biology-2018

Theme: Exploring Life, Inspiring Innovation, Creating Future
Time: October 14 - 16, 2018
Venue: Fukuoka, Japan


Registration
Time: 09:00 -20:00, October 13, 2018 (Saturday); Place: Lobby, 1st Floor, Hilton Fukuoka Sea Hawk, Japan
Time: 09:00 -17:00 October14-15, 2018; Place: Lobby, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan

 

Opening Ceremony

Time: 09:00 -09:10, October 13, 2018 (Saturday); Place: Navis, 1st Floor, Hilton Fukuoka Sea Hawk, Japan

 

 

Keynote Forum Part I
Time: 09:10-10:30, October14, 2018 (Sunday); Place: Navis, 1st Floor, Hilton Fukuoka Sea Hawk, Japan
Moderator
Dr. Nick Zhang, Chairman and CEO, QIAGEN (Suzhou) Translational Medicine Co. Ltd., China
09:10-09:15
Moderator's Introduction
09:15-09:40
Title: Left or Right Snail Shell Coiling Determined by a Single Gene- Mechanogenetics and Gene Editing
Dr. Reiko Kuroda, 
Professor, Tokyo University of Science, Japan
09:40-10:05
Title: Microglia in Neuropathic Pain: Mechanisms Andtherapeutic Potentialing
Dr. Kazuhide Inoue, Professor,Kyushu University, Japan
10:05-10:30
Title: CG-806, a First-in-Class Pan-FLT3/Pan-BTK Inhibitor, Demonstrates Superiority to Other FLT3 and BTK Inhibitors against Primary Patient Samples
Dr. William G. Rice, Chairman, President and CEO, Aptose Biosciences Inc., USA

 

Keynote Forum Part II
Time: 09:00-10:25, October15, 2018 (Monday); Place: Navis, 1st Floor, Hilton Fukuoka Sea Hawk, Japan
Moderator
Dr. Dan Pettersson, Science Manager, Novozymes A/S, Denmark
09:00-09:05
Moderator's Introduction
09:05-09:35
Title: Models, Molecules and Man:Basic Research and the Conquest of Disease
Dr. Tim Hunt
, Emeritus Group Leader, Clare Hall Laboratories, UK
Nobel Prize laureate in Physiology or Medicine, 2001
09:35-10:00
Title: A Novel Genetically Engineered Hematopoietic Blood System Conferring Tumor Resistance and Healthy Longevity
Dr. C.-K. James Shen, Distinguished Research Fellow, Academia Sinica, Taiwan
10:00-10:25
Title: Successful Commercialization of Autologous Cell Therapy: Incremental Improvement or Radical Changes
Dr. Behzad Mahdavi, VP Strategic Innovation & Alliances, Lonza Walkersville, Inc., USA


Theme 1: Frontiers in Molecular & Cell Biology

Theme 101: DNA Methylation, Chromatin and Epigenetics
Time: 10:30-12:15, October 14, 2018 (Sunday); Place: KEI, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Mohamad Eid Hammadeh, Professor, Saarland University, Germany
10:30-10:35
Chair's Introduction
10:35-10:55
Title: Impact of Cigarette Smoking on Sperm DNA Methylation by Patients Undergoing ART Treatment
Dr. Mohamad Eid Hammadeh, Professor, Saarland University, Germany
10:55-11:15
Title: Molecular Regulation of Dynamic Epigenetic Changes at Key Embryonic Transitions in the Early Embryo
Dr. Y. Li, 
Research Fellow, The University of Sydney, Australia
11:15-11:35
Title: Uncovering New Roles of Chromatin: Control of Gene Activation and Splicing by Testis-specific Histone Variant, mH2A.B3
Dr. Tatiana A. Soboleva, Senior Scientist, The Australian National University, Australia
11:35-11:55
Title: Novel Effects of Metal Cations on Nucleic Acids, Chromatin and Undifferentiated State of ES Cells
Dr. Takashi Ohyama, 
Professor, Waseda University, Japan
11:55-12:15

Title: Two Histone Demethylases KDM7A and UTXsynergistically Modulate Chromatin Conformation to Control Inflammation in Human Endothelial Cells

Dr. Yasuharu Kanki, Assistant Professor, The University of Tokyo, Japan

 

Theme 102: Protein Structure and Function
Time: 13:30-15:15, October 14, 2018 (Sunday); Place: YOH, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Athina Zouni, Professor, Humboldt-Universität zu Berlin, Germany
13:30-13:35
Chair's Introduction
13:35-13:55
Title: Involvementof P2X7 Intothe Alveolar Barrierfunction after Lung Injury
Dr. Michael Kasper, Professor, Institute of Anatomy,  Medical Faculty, TU Dresden, Germany
13:55-14:15
Title: Resveratrol Inhibits NADPH Oxidase Activity: Involvement of SIRT1-mediated Rac1 Deacetylation
Dr. Ning Xia, Project Leader, Johannes Gutenberg University Medical Center, Germany
14:15-14:35
Title: Insights into an Apo-Photosystem II Structure: Assembly and Disassembly of the Water-splitting Cofactor 
Dr. Athina Zouni, Professor, Humboldt-Universität zu Berlin, Germany
14:35-14:55
Title: Mass Spectrometry of Mitochondrial Protein Complexes
Dr. Claire Lemaire, Senior Researcher, CNRS URA 9198 – I2BC -B3S – LPSM, CEA Saclay, 91191 Gif-sur-Yvette Cedex, France
14:55-15:15
Title: MCPIP1 as an RNase Controlling Stability of RNA Templates
Dr. J. Jura ,  Professor, Jagiellonian University, Poland

 

Theme 103: Mitochondrial Function and Cell Energy Metabolism
Time: 10:35-12:40, October 15, 2018 (Monday); Place: KEI, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Chair: Dr. Chiung-Mei Chen, Professor, Chang Gung Memorial Hospital, Chang Gung University, Taiwan
10:35-10:40
Chair's Introduction
10:40-11:00
Title: Alternations of Metabolic Profile and Kynurenine Metabolism in the Plasma of Parkinson’s Disease
Dr. Chiung-Mei Chen, Professor, Chang Gung Memorial Hospital, Chang Gung
University, Taiwan
11:00-11:20
Title: Mitochondrial Stress Signaling Induces Telomere Attrition and 
Chromosomal DNA Damage through Altered Histone Acetylation
Dr. Narayan G. Avadhani, Professor, University of Pennsylvania, USA
11:20-11:40
Title: Design of a Unique Atmosphere-mimicking Exposure Device for Investigating Oxidative Stress, Inflammatory and Cardiometabolic Effects of Nanosized Pollutants in Rodents
Dr. Sylvia Pietri, Professor, Aix Marseille University, CNRS, Marseille, France
11:40-12:00
Title: Gender Differentials of Metabolic Syndrome in Bangladesh
Dr. Syed Muhammad Baqui Billah, Assistant Professor, Sulaiman Al Rajhi Colleges, Al Qassim, Saudi Arabia
12:00-12:20
Title: Correlation between Nuclear DNA Fragmentation, Mitochondrial DNA Damage and Standard Sperm Parameters in Human Spermatozoa of Fertile and Sub-fertile before and after Freeze-thawing Procedure
Dr. Houda Amor, Scientific Assistant, Saarland UniversityGermany
12:20-12:40

Title: Abnormal Mitochondrial Calcium Uptake in the Brain Stem Neuron of Ndufs4 Knockout Mice

Dr. Shangcheng Xu, Associate Professor, Chongqing Sixth People Hospital & Chongqing University, China

 

Theme 104: Signal Transduction, Cytokine & Growth Factors
Time: 10:35-12:00, October 15, 2018 (Monday); Place: YOH, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Billy KC Chow, Professor, University of Hong Kong, Hong Kong, China
10:35-10:40
Chair's Introduction
10:40-11:00
Title: Structure and Signaling of Secretin Receptor in Water and Blood Pressure Control
Dr. Billy KC Chow, Professor, University of Hong Kong, Hong Kong, China
11:00-11:20
Title: Prenatal and Perinatal Factors in Predicting Criminality
Dr. Stephen G. Tibbetts, Professor, California State University, San Bernardino, USA
11:20-11:40
Title: ROCO Family Kinase LRRK1 Regulates the Transport and Maturation of EGFR-containing Endosomes
Dr. Hiroshi Hanafusa, Associate Professor, Nagoya University,Japan
11:40-12:00
Title: Notch Signaling Pathway and Resistance to Androgen Deprivation Therapy (ADT) for Prostate Cancer
Dr. Yu-Xiang Fang, Associated Investigator, Shanghai Jiao Tong University, China

 

Theme 105: Cell Cycle, Cell Death, Autophagy, Cell Stress
Time: 13:30-16:30, October 15, 2018 (Monday); Place: KEI, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Jian Liu, Principal Investigator, National Institutes of Health; Associate Professor, Johns Hopkins University, USA
13:30-13:35
Chair's Introduction
13:35-13:55
Title: Protection against LPS-induced Liver Injury by Stimulating Autophagy through NAADP-mediatedCa2+ Signaling
Dr. Uh-Hyun Kim, Professor, Chonbuk National University Medical School, South Korea
13:55-14:15
Title:  Two Distinct Actin Networks Drive Traction Oscillation to Confer Focal Adhesion Mechanosensing
Dr. Jian Liu, Principal Investigator, National Institutes of Health; Associate Professor, Johns Hopkins University, USA
14:15-14:35
Title:  MiR-146a Protects Small Intestine against Ischemia/Reperfusion Injury by Down-regulating TLR4/TRAF6/NF-κB Pathway
Dr. Xiangyu Zhou, Professor, Southwest Medical University, China
14:35-14:55
Title: N-Acetyl-Glucosamine Sensitizes Non-Small Cell Lung Cancer Cells to TRAIL InducedApoptosis by Activating Death Receptor 5
Dr. Ye Liang, Associate Researcher, Affiliated Hospital of Qingdao University, China
14:55-15:15
Title: Calcium Signals in Subcellular Compartments Control Life and Death of Cancer Cells
Dr. Arkadiusz Orzechowski, Professor, Warsaw University of Life Sciences – SGGWPoland
15:15-15:30
Coffee Break
15:30-15:50
Title: Regulation of Autophagy by Sex Steroids in Bovine Mammary Gland
Dr. Malgorzata Gajewska, Associate Professor, Warsaw University of Life Sciences, Poland
15:50-16:10
Title: A Recursive Vesicle-based Model Protocell

Dr. Tadashi Sugawara, Professor, Kanagawa University, Japan

16:10-16:30

Title: Prion Protein-mediated Calcium Overload Induces Neuron Celldeath through AMPK Signals

Dr. Sang-Youel Park, Professor, Chonbuk National University, South Korea

 

Theme 106: Cell Biology in Immunology
Time: 13:30-15:15, October 15, 2018 (Monday); Place: YOH, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Lixin Liu, Associate Professor, University of Saskatchewan, Canada
13:30-13:35
Chair's Introduction
13:35-13:55
Title: Understanding the Role of Leukocyte-specific Protein 1 (LSP1) in Neutrophil Recruitment
Dr. Lixin Liu, 
Associate Professor, University of Saskatchewan, Canada
13:55-14:15
Title: The Functional Regulation of Tristetraprolin Family in Mouse RAW264.7 Macrophages
Dr. Ching-Jin Chang, Associate Research Fellow, Academia Sinica, Taiwan
14:15-14:35
Title: Role of MCPIP1 in the Skin Inflammation
Dr. A. Lichawska-Cieslar, Postdoctoral Researcher, Jagiellonian University, Poland
14:35-14:55
Title: Oxidative and Nitrosative Stress in Neutrophils
Dr. Urszula Demkow, Head, Medical University of Warsaw, Poland
14:55-15:15
Title: Cancer Immunotherapy: Progress And Challenges
Dr. Jinru Shia,
 Professor, Weill Cornell Medical College, USA

 

Theme 107: Microbial Cell Biology, Molecular and Cellular Parasitology
Time: 13:30-15:35, October 15, 2018 (Monday); Place: KOH, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Chih-Wen Peng, Professor, Institute of Medical Sciences, Tzu Chi University, Taiwan
13:30-13:35
Chair's Introduction
13:35-13:55
Title: How an Oncolytic Virus Exploits Cellular Machineries to Establish Persistency in Host Cells
Dr. Chih-Wen Peng, Professor, Institute of Medical Sciences, Tzu Chi University, Taiwan
13:55-14:15
Title: Environment Pollution and Gene Mutation Correlation
Dr. Chiung fang Peng, CEO, Fuga Biotechnology Company; President, Taiwan Academy of Ecologic Hazard &Health Management, Taiwan
14:15-14:35
Title: Fibronectin Receptors Expressed on Clostridium Perfringens Cells
Dr. Yasuo Hitsumoto,
 Professor, Okayama University of Science, Japan
14:35-14:55
Title: Dietary Replacement of Marine Ingredients by Terrestrial Animal and Plant Alternatives Modulates the Antiviral Response of Atlantic Salmon (Salmo salar)
Dr. R. G. Taylor, Cell Biologist, Cargill Animal Nutrition, USA
14:55-15:15 Title: Landmarks of Endosomal Remodeling in the Early Phase of Cytomegalovirus Infection
Dr. Pero Lu�in, Professor, University of Rijeka, Croatia
15:15-15:35
Title: An Alternative Approach to Treat Extensively-drug-resistant Gram-negative Bacterial Pathogens
Dr. Dong H. Kwon, Associate Professor, Long Island University, USA 

 

Theme 108: Physiology and Molecular Biology of Plants
Time: 08:30-10:15, October 16, 2018 (Tuesday ); Place: KEI, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Raimund Fromme, Associate Research Professor, Arizona State University, USA
08:30-08:35
Chair's Introduction
08:35-08:55
Title: What Can We Learn From the High Resolution Structure of the Heliobacterial Photosystem and Photosystem I of Cyanobacteria in Respect of Evolution of Photosynthesis and Nanotechnology
Dr. Raimund Fromme, Research Associate Professor, Arizona State University, USA
08:55-09:15
Title: Search for the Sex-determination Gene in Asparagus officinalis
Dr. Kohji Murase, Associate Professor, The University of Tokyo, Japan
09:15-09:35
Title: Safe and Reproducible Alternatives for Taxans Production 
Dr. Faezeh Ghanati, Professor, Tarbiat Modares University, Iran
09:35-09:55
Title: The Novel Mechanism for Plant Drought Tolerance  
D. Jong-Myong Kim,  Associate Professor, The University of Tokyo, Japan
09:55-10:15

Title: Utilization of next-generation sequencers for understanding plant genetic structure by chloroplast DNA analysis

Dr. Hiroyuki Kurokochi, Assistant Professor, The University of Tokyo, Japan

 

Theme 109: Intracellular Trafficking, Cell Organelles and Membranes
Time: 08:30-10:35, October 16, 2018 (Tuesday ); Place: YOH, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Alexander Ludwig, Senior Research Fellow, Nanyang Technological University, Singapore
08:30-08:35
Chair's Introduction
08:35-08:55
Title: Peroxisome Homeostasis and Human Disorders
Dr. Yukio Fujiki, Professor, Medical Institute of Bioregulation, Kyushu University, Japan
08:55-09:15
Title: Molecular and Spatial Organization of the Epithelial Apical Polarity Network Studied by Quantitative Proximity Proteomics and High-resolution Electron Microscopy
Dr. Alexander Ludwig, Senior Research Fellow, Nanyang Technological University, Singapore
09:15-09:35
Title: Sec5/GEF-H1 Interaction, A New Target for Cancer Cell Migration
Dr. Céline DerMardirossian, Associate Professor, Scripps Research, USA
09:35-09:55
Title: A Molecular Ensemble in the rER for Post-translational Modifications and Folding of Procollagen
Dr. Yoshihiro Ishikawa, Shriners Hospitals for Children Portland, USA
09:55-10:15
Title: Emergence of Left-right Asymmetry in Single Cell and Cell Groups
Dr. Yee Han Tee, Senior Research Fellow, National University of Singapore, Singapore
10:15-10:35

Title: Heterocyclic Sterol Probes for Live Monitoring of Sterol Trafficking and Lysosomal Storage Disorders

Dr. Jarmila Královát, Senior Scientist, Institute of, Molecular Genetics of the ASCR, Prague, Czech Republic

 

Theme 110: DNA Replication, Recombination and Repair
Time: 13:30-14:55, October 16, 2018 (Tuesday ); Place: KEI, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Martin Falk, Head, Institute of Biophysics, The Czech Academy of Sciences, Czech Republic
13:30-13:35
Chair's Introduction
13:35-13:55
Title: DNA Unwinding by Viral Protein R induces DNA Double-strand Breaks and Contributes to HIV Infection into Resting Macrophages
Dr. Yukihito Ishizaka, Director, National Center for Global Health and Medicine, Japan
13:55-14:15
Title: DNA Damage and Repair in Normal and Tumor Cells upon Cell Exposure to Ionizing Radiation of Different Quality
Dr. Martin Falk, Head, Institute of Biophysics, The Czech Academy of Sciences, Czech Republic
14:15-14:35
Title: Transposon-driven Life Cycle of W / Y Chromosome – The Hypothesis and Relevant Literature Review
Dr. Ewa B. SliwinskaAssistant Professor, Institute of Nature Conservation of the Polish Academy of Sciences, Poland
14:35-14:55
Title: Are Myelodysplastic Syndromes (MDS) a Chromatin Structure Disease
Dr. Iva Falková, Researcher, Institute of Biophysics, Academy of Science of CR v.v.i., Brno, Czech Republic

 

Theme 111: Omics and Bioinformatics 
Time: 13:30-16:50, October 16, 2018 (Tuesday ); Place: YOH, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Anthony Berdis, Associate Professor, Cleveland State University, USA
13:30-13:35
Chair's Introduction
13:35-13:55
Title: Anti-tumor Effects of Orally Administered Chitin and Chitosan Oligosaccharides
Dr. Yoshiharu Okamoto, Professor, Tottori University, Japan
13:55-14:15
Title: Species and Tissues Specific Differentiation of Processed Animal Proteins (PAPs) in Meat and Bone Meals and Aquafeeds Using Proteomics Tools 
Dr. Martine Raes, Full Professor, University of Namur, Belgium
14:15-14:35
Title: Artificial Nucleosides and Nucleotides: Applications as Diagnostic and Therapeutic Agents against Cancer
Dr. Anthony Berdis, Associate Professor, Cleveland State University, USA
14:35-14:55
Title: A New Search Subspace to Compensate Failure of Cavity-based Localization of Ligand-binding Sites
Dr. Kalpana Singh, Research Associate, CCS University, India
14:55-15:15
Title: Sphingolipid Signaling and Neuronal Function
Dr. Shun-ichi Nakamura, Professor, Kobe University Graduate School of Medicine, Japan
15:15-15:30
Coffee Break
15:30-15:50
Title: Drosophila Transglutaminase-A is Secreted Viaan Unconventional Pathway Involving two Types of Fatty Acylations and Exosomes
Dr. Toshio Shibata, Assistant Professor, Kyushu University, Japan
15:50-16:10
Title: Analysis of the Complete Mitogenome of purpureocillium sp. Udea0106 Strain and Its Relationship with Hypocreales Biocontrollers Fungi 
Dr. Nadya L. Cardona, Leader,  Instituto de Biología-Universidad de Antioquia Medellín,Universidad EAFIT, Colombia
16:10-16:30
Title: Diploid Genetic Algorithms for Solving Complex Optimization Problems
Dr. Petrica Pop Sitar, Professor, Technical University of Cluj-Napoca, North University Center at Baia Mare, Romania
16:30-16:50
Title: Computational Identification & Screening for Deleterious Mutants
Dr. Andrzej Kloczkowski, Professor, Nationwide Children’s Hospital and The Ohio State University, USA


Theme 2: Stem Cells and Regenerative Medicine 

Theme 2: Stem Cells and Regenerative Medicine
Time: 13:30-16:30, October 15, 2018 (Monday); Place: KIKU, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Shimon Efrat, Professor, Tel Aviv University, Israel
Co-chair
Dr. Gulinnaz Ercan, Professor, Ege University School of Medicine, Turkey
13:30-13:35
Chair's Introduction
13:35-13:55
Title: Anti-tumor Effects of Cordycepin: Disrupts Leukemia Association With Mesenchymal Stem Cells, Eliminates Angiogenesis and Suppresses Tumor Progressionof Hepatocellular Carcinoma
Dr. Jun-Yang Liou, Associate Investigator, National Health Research Institutes, Taiwan
13:55-14:15
Title: Open Chromatin Structure in iPS Cells is Associated with Enhanced Differentiation into Pancreas Progenitors
Dr. Shimon Efrat, Professor, Tel Aviv University, Israel
14:15-14:35
Title: The Expression Level of CHD7 is Related to the Differentiation Potential
Dr. Shin Kawamata, Director, Research and Development Center for Cell Therapy at Foundation for Biomedical Research and Innovation (FBRI), Japan
14:35-14:55
Title:  Stem Cell Manufacturing Scale up Issues
Dr. Alex Kharazi, CTO, Stemedica Cell Technologies, USA
14:55-15: 15

Title: Human Umbilical Cord Blood Stem Cell Therapy for Amyotrophic Lateral Sclerosis (ALS)
Dr. Dianrong Gong, Professor& Director, Department of Neurology, Liaocheng People’s Hospital, Taishan Medical University, China

15:15-15:30
Coffee Break
15:30-15:50
Title: Browning of different Stem Cells: UCB-MSCs and AD-MSCs
Dr. Gulinnaz Ercan, ProfessorEge University School of MedicineTurkey
15:50-16:10
Title: The Amphycultural Diffusion Capsules as a Modern Methodological Approachin Assessment of Hematopoietic Stem Cells Regeneration
Dr. Bilko Nadiia, Head, National University 'Kyiv-Mohyla Academy', Ukraine
16:10-16:30
Title: Development and Evaluation of Biocompatible Collagen/HA Porous Composite Scaffolds for Bone Tissue Engineering
Dr. Shariful Islam Associate Professor, University of Rajshahi, Bangladesh


Theme 3: Advanced Technologies for Molecular & Cell Biology

Theme 3: Advanced Technologies for Molecular & Cell Biology
Time: 13:30-17:10, October 15, 2018 (Monday); Place: RAN, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Kentaro Doi, Associate Professor, Osaka University, Japan
Co-Chair

Dr. Katsuyuki Shiroguchi, Unit Leader, RIKEN Center for Biosystems Dynamics Research(BDR), RIKEN for Integrative Medical Sciences (IMS)& PRESTO JST, Japan

13:30-13:35
Chair's Introduction
13:35-13:55
Title: Modeling of Electrokinetic Transport of ssDNA and dsDNA in Micro- and Nanofluidic Channels
Dr. Kentaro Doi, Associate Professor, Osaka University, Japan
13:55-14:15
Title: New Sensitive Targeted pH Probes for Mitochondrial, Acidic and Cytosolic pHs Determination by 31-P NMR and EPR
Dr. Marcel Culcasi, Professor, Aix Marseille University, CNRS, Marseille , France
14:15-14:35
Title: Tracking FGF21 Traffic inside Intact Human Cells by Cryo-Electron Tomography
Dr. Maia Azubel, Stanford University School of Medicine, USA
14:35-14:55
Title: Superresolution Multimodal Optical System used for Nanoscale Biological Investigations
Dr. George A. Stanciu, Professor, University Politehnica of Bucharest, Romania
14:55-15:15
Title: Free-floating Single Cellimaging by Using Integrated Dual-mode Tomography
Dr. Yu-Chih Lin, Postdoctoral Researcher, National Taiwan Normal University, Taiwan
15:15-15:30
Coffee Break
15:30-15:50

Title: A Novel Method for the High Throughout Analysis of Bacterial Microbiota: Bacteria Identification with the Single-base Accuracy and Bacteria Quantification at the Single-cell Level

Dr. Katsuyuki Shiroguchi, Unit Leader, RIKEN Center for Biosystems Dynamics Research(BDR), RIKEN for Integrative Medical Sciences (IMS)& PRESTO JST, Japan

15:50-16:10
Title: The Microfluidic Platform for Personalized Medicine and Healthcare
Dr. Nien-Tsu Huang, Associate Professor, National Taiwan University, Taiwan
16:10-16:30
Title: Segmentation and Tracking of Stem Cells in Time Lapse Microscopy to Quantify Dynamic Behavioral Changes during Spheroid Formation
Dr. Ching-Fen Jiang, Professor, I-Shou University, Taiwan
16:30-16:50
Title: Cryo-EM: From ‘blobology’ to High-Resolution Structures in Less Than A Decade
Dr. Natalia de Val, Director, Electron Microscopy Laboratory, Team Lead, Cryo-EM, Center for Molecular Microscopy, Frederick National Laboratory for Cancer Research, National Cancer Institute (NCI), National Institute of Health (NIH), Leidos Biomedical Research, Inc., USA
16:50-17:10

Title: Novel Pentamethinium Salt for Targeting Mitochondria: from Imaging to Theranostics

Dr. Vladimír Král, Professor, Charles University, Czech Republic


Theme 4: Molecular & Cell Biology in Drug R & D and Medicine

Theme 401: Role of Molecular & Cell Biology in Translational Medicine
Time: 13:30-15:35, October 14, 2018 (Sunday); Place: KOH, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Irene Caesar, CEO, Matrix Ltd., Russia; President, Wave Genome, USA
Co-Chair
Dr. Warren Ladiges, Professor, University of Washington, USA
13:30-13:35
Chair's Introduction
13:35-13:55
Title: Molecular Pathways of Aging are Translational Drug Targets for Alzheimer’s Disease
Dr. Warren Ladiges, Professor, University of Washington, USA
13:55-14:15
Title: Mesenchymal Stem Cell Derived Microvesicles Modulate Microglia Cells
Dr. Frank Emmrich, Professor, Fraunhofer Institute for Cell Therapy and Immunology,Germany
14:15-14:35

Title: Remote Management of Biosystems via Holographic Embryo Based upon the Wave Optics of Chromosomes as Modulated Scalar Wave Diffraction Grating

Dr. Irene Caesar, CEO, Matrix City LLC, Russia; President, Wave Genome LLC, USA

14:35-14:55
TitleEnhancement of Curcumin Bioavailability and Biological Activities: Roles of Molecular and Cell Biology in Prodrug Development
Dr. Pornchai Rojsitthisak, Associate Professor, Chulalongkorn University, Thailand
14:55-15:15
Title: Inhibited Early Immunologic Response Is Associated with Hypertrophic Scarring
Dr. Frank Niessen,
 Plastic Surgeon, Amsterdam University Medical Center, Netherlands
15:15-15:35
Title: Assessment of Safety and Efficacy of Phytoestrogen, Isoflavone, On Bone Metabolism in Animal Models
Dr. Yoshiko Ishimi, Senior Adviser, Chief Researcher, National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Japan

 

Theme 402: Research of Molecular Drug Target and Biomarker
Time: 13:30-14:55, October 14, 2018 (Sunday); Place: KIKU, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Nick Zhang, Chairman and CEO, QIAGEN (Suzhou) Translational Medicine Co. Ltd., China
13:30-13:35
Chair's Introduction
13:35-13:55
Title: Biomarker and Companion Diagnostics in Precision Medicine
Dr. Nick Zhang, Chairman and CEO, QIAGEN (Suzhou) Translational Medicine Co. Ltd., China
13:55-14:15
Title: Novel Understanding of Sepsis Pathophysiology Based on Dynamics of Plasma Protein Histidine-rich Glycoprotein and A Proposal of Treatment

Dr. Masahiro Nishibori, Professor, Okayama University, Japan

14:15-14:35
Title: Large Scale Cell Expansion. Novel Approach of Bioreactor Process Control
Dr. Eriks Jakobsons, Head of Cell Transplantation Centre, Pauls Stradins Clinical University HospitalLatvia
14:35-14:55
Title: Suppression of Targeting of Dbf4-dependent Kinase to Pre-replicative Complex in G0 Nuclei
Mr. Takuya Okada,Kyoto University, Japan

 

Theme 403: Cancer Cell Biology Part I
Time: 14:55-17:20, October 14, 2018 (Sunday); Place: KIKU, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Chair: Dr. Lunawati Bennett,  Professor, Union University College of Pharmacy, USA
14:55-15:00
Chair's Introduction
15:00-15:20
Title: APTO-253 Inhibits MYC Expression and Induces DNA Damage in Acute Myeloid Leukemia Cells by Stabilizing G-Quadruplex DNA Motifs
Dr. William G. Rice, Chairman, President and CEO, Aptose Biosciences Inc., USA
15:20-15:40
Title: Intratumoral Heterogeneity in Germ Cell Tumor of the Testis: Cellular vs Genetic Origin of Cancer
Dr. Shi-Ming Tu, Professor, University of Texas MD Anderson Cancer Center, USA
15:40-16:00
Title: Vitamin C Effect on Certain Cancer Cell Lines 
Dr. Lunawati Bennett,  Professor, Union University College of Pharmacy, USA
16:00-16:20
Title: The Human Genome Project and the Discovery of AZQ (US Patent 4,146,622) Specifically Designed for Treating Brain Cancer
Dr. A. Hameed Khan, Senior Scientist, National Institutes of Health (NIH), USA
16:20-16:40
Title: Cancer Detection, Therapy and Screening Using 5-aminolevulinic Acid
Dr. Tohru Tanaka, Director, Executive Officer, CTO, SBI Pharmaceuticals Co. Ltd.; Professor, Keio University, Japan
16:40-17:00
Title: Borojoapatinoi Cell Culture for the Production of Compounds with Anticancerogenic Activity
Dr. Rodrigo A. Hoyos Sanchez, Professor, Universidad Nacional de Colombia, Sede Medellin, Colombia
17:00-17:20
Title: Intracellular Cholesterol Homeostasis: A Comparison Between Carcinogen-Exposed Cells and Cancer Tumour
Dr. Nimai Chand Chandra, Professor, All India Institute of Medical Sciences, India

 

Theme 404: Cellular Neurobiology and Neurodegeneration
Time: 13:30-16:30, October 14, 2018 (Sunday); Place: RAN, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Kimiko Inoue, Director, Toneyama National Hospital, Japan
Co-Chair
Dr. Lian Li, Professor & Vice Chair, Emory University, USA
13:30-13:35
Chair's Introduction
13:35-13:55
Title: Neuropathology of Neuronal Intermediate Filament Inclusion Disease (NIFID)
Dr. Kimiko Inoue, Director, Toneyama National Hospital, Japan
13:55-14:15
Title: Hyperbaric Oxygen Treatment of Chronic Pain and Suppression of Opioid Withdrawal
Dr. Raymond M. Quock, Professor, Washington State University, USA
14:15-14:35
Title: The Role of Astrocyte Alterations in Early Changes in the Dynamics of Cultured Cerebellar Networks
Dr. Ari Barzilai, Professor, Tel Aviv University, Israel
14:35-14:55

Title: Protein Kinase and the Chronification of Acute Pain: Synaptic Homeostasis and the Neuropathic Process

Dr. Daryl I. Smith, Associate Professor, University of Rochester School of Medicine and Dentistry, USA

14:55-15:15
Title: Drug Effects on Neurodegeneration in Niemann-pick Type C1 Disease
Dr. Jiankai Luo, Principle Investigator, University of Rostock, Germany
15:15-15:30
Coffee Break
15:30-15:50
Title: Neural Stem Cells for Brain Repair and Regeneration
Dr. Dong Sun, Associate Professor, Virginia Commonwealth University, USA
15:50-16:10
Title: Inhibition of Y1 Receptor in Beta Cells Increases Insulin Secretion and Improves Islet Transplant Efficiency
Dr. Yanchuan Shi, Group Leader, Neuroendocrinology, Neuroscience Division, Garvan Institute of Medical Research, Australia
16:10-16:30
Title: Network-Based Discovery of Alzheimer’s Disease Pathways and Therapeutic Targets
Dr. Lian Li, Professor & Vice Chair, Emory University, USA

 

Theme 405: Cardiovascular and Cerebralvascular Disease
Time: 15:35-17:20, October 14, 2018 (Sunday); Place: YOH, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Bella Koifman, Director, Women's Heart Clinic, Tel Aviv Sourasky Medical Center, Israel
15:35-15:40
Chair's Introduction
15:40-16:00
Title: Database Evaluation of the Association between Serum Magnesium Levels and the Risk of Atrial Fibrillation in the Community
Dr. Ronen Loebstein, Associate Professor,  Institute of Clinical Pharmacology, Sheba Medical Center, Tel Aviv University, Israel
16:00-16:20
Title: Untilization of Felbamate, NMDA Receptor Blocker, For Resuscitation of Post-cardiac Arrest Anoxic Encephalopathy after Failure of Hypothermia
Dr. Hisanori Hasegawa, Assistant Professor, University of South Carolina School of Medicine in Greenville, USA
16:20-16:40
Title: Novel Therapeutic Approach in Atherosclerotic Cardiovascular Disease
Dr. Bella Koifman, Director, Women's Heart Clinic, Tel Aviv Sourasky Medical Center, Israel
16:40-17:00
Title: Identification of the Novel Signaling Pathway Regulating Both Abnormal Ca2+-independent Contraction and Cell Migration of Vascular Smooth Muscle
Dr. Sei Kobayashi, Professor and Chairman, Yamaguchi University, Japan
17:00-17:20
Title: KLF2-induced Exosomal microRNA Delivery: Potential Implications in Treatment of Pulmonary Hypertension
Dr. Beata Wojciak-Stothard, Senior Lecturer, Imperial College London, UK

 

Theme 406: Aging and Aging-related Disease
Time: 15:30-16:55, October 15, 2018 (Monday); Place: YOH, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Andrew CK Law, Professor of Psychiatry, Royal College of Surgeons in Ireland at Perdana University, Malaysia
15:30-15:35
Chair's Introduction
15:35-15:55
Title: In Finding that Elusive Magic Bullet… Are You a Dreamer or a Realist
Dr. Andrew CK Law, Professor of Psychiatry, Royal College of Surgeons in Ireland at Perdana University, Malaysia
15:55-16:15
Title: The Effects of Ageing on Cholesterol Metabolism in the CNS
Dr. Doug Smith, Associate Professor, University of Newcastle, Australia
16:15-16:35
Title: The Role of Androgens in Age-related Vascular Repair and Regeneration 
Dr. Yuen Ting Lam, Postdoctoral Research Scientist, Heart Research Insitute, Australia
16:35-16:55

Title: Age-related Changes in Cyclic Phosphatidic Acid (cPA)-induced Hyaluronic Acid Synthesis in Human Fibroblasts

Dr. Katsura SANO, Material Research Manager, Research and Development Division, ALBION CO., LTD., Japan

 

Theme 407: Hematology
Time: 15:30-17:55, October 16, 2018 (Tuesday ); Place: KEI, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Rahima Zennadi, Associate Professor, Duke University Medical Center, USA
15:30-15:35
Chair's Introduction
15:35-15:55
Title: Rivaroxaban Treatment for Warfarin-Refractory Thrombosis in a Patient with Hereditary Protein S Deficiency
Dr. Koken Ameku, Physician, Okinawa Prefectural Nanbu Medical Center & Children’s Medical Center, Japan
15:55-16:15
Title: Role and Regulation of Sickle Red Cell Interactions with Endothelial Cells Leading to Vaso-occlusion in Sickle Cell Disease
Dr. Rahima Zennadi, Associate Professor, Duke University Medical Center, USA
16:15-16:35
Title: HLA-DQB1 / HLA-B Genotype-guided Schedules and Intensive Blood Monitoring in Patients Taking Clozapine: A Cost-effectiveness Analysis.
Dr. François R. GIRARDIN, Medical Doctor, The University Hospitals of Geneva,Switzerland
16:35-16:55
Title: Total Protein S Assay System: Clinical Significance and Pre-analytical Quality Control
Dr. Hiroko Tsuda,Professor, Nakamura Gakuen University, Japan
16:55-17:15
Title: What is the Relation between CD47 and Sickled Red Blood Cells
Dr. Nawal Helmi, Assistant Professor, King Abdulaziz University, JeddahUniversity, Saudi Arabia
17:15-17:35
Title: The Relationship between the Period of Erythrocytes Storage, Erythrophagocytosis and the Amount of Erythrocyte Microvesicles
Dr. Anna Stachurska, Medical Centre of Postgraduate Education,  Poland
17:35-17:55
Title: Antagonistic Receptor Protein-tyrosine Phosphatases DEP-1 and CD45 Aggravate Myeloproliferative Phenotype of FLT3-ITD Mice
Dr. Anne Kresinsky, Friedrich Schiller University, Germany

 

Theme 408: Cancer Cell Biology Part II
Time: 13:30-17:50, October 16, 2018 (Tuesday ); Place: KOH, 3rd Floor, Hilton Fukuoka Sea Hawk, Japan
Chair
Dr. Xiaoyan Jiang, Senior Scientist & Professor, British Colombia Cancer Agency and University of British Colombia , Canada
Co-Chair

Dr. Adel A. El-Naggar, Professor, UT MD Anderson Cancer Center, USA

13:30-13:35
Chair's Introduction
13:35-13:55
Title: Understanding Human Health and Disease with LC/MS Based Metabolic Phenotyping
Dr. 
Charles Theillet, Professor, INSERM U1194, Montpellier, France
13:55-14:15
Title: Characterization of Small Extracellular Vesicles, Exosomes, As a Novel Drug Delivery Vehicle for Proteins
Dr. Kunihiro Tsuchida, Professor, Fujita Health University, Japan
14:15-14:35
Title: Establishment of a Dog Primary Prostate Cancer Organoid Using the Urine Cancer Stem Cells
Dr. Tatsuya Usui, Appointed Lecturer, Tokyo University of Agriculture and Technology, Japan
14:35-14:55
Title: Patient-derived High Grade Serous Ovarian Cancer Cell Lines: Models to Understand Molecular Mechanisms of Disease Progression
Dr. Dan Cacsire Castillo-Tong, Associate Professor, Medical University of Vienna, Austria
14:55-15:15

Title: Targeting Cancer Metastasis via Novel Drug Development
Dr. Chao-Nan (Miles) Qian, Professor, Sun Yat-sen University Cancer Center, China

15:15-15:30
Coffee Break
15:30-15:50
Title: Double Rolling Circle Replication (DRCR): A Mode of Amplification of Oncogene as well as Drug-resistant Genes and Replication of HSV and Chloroplast DNA
Dr. Takashi Horiuchi, Professor, Tokai University School of Medicine, Japan
15:50-16:10
Title: A Novel Treatment Approach to Selectively Target Drug-resistant Cancer Stem Cells
Dr. Xiaoyan Jiang, Distinguished Scientist, Terry Fox Laboratory, BC Cancer Research Centre ; Professor, University of British Colombia, Canada
16:10-16:30

Title: Prognostic Biomarkers in Nasopharyngeal Cancer

Dr. Jack Phan, Associate Professor, University of Texas MD Anderson Cancer Center, USA

16:30-16:50

Title: Phospholipase C-related Catalytically Inactive Protein, A Phosphatidylinositol Metabolism Regulator, Controls The Metastatic Potential in Breast Cancer Cells

Dr. Takashi Kanematsu, Professor, Hiroshima University, Japan

16:50-17:10

Title: A Pan-cancer Analysis Reveals High-frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily
Dr. Rehan Akbani, Associate Professor, The University of Texas MD Anderson Cancer Center, USA

17:10-17:30

Title: The Prognostic Value of NRF2 in Solid Tumor Patients

Dr. Chunze Zhang, Associate Professor, Tianjin Union Medical Center, China

17:30-17:50

Title: Conventional and Viral-Associated Head and Neck Squamous Carcinoma: Molecular and Biological Features

Dr. Adel A. El-Naggar, Professor, UT MD Anderson Cancer Center, USA

 


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